KMID : 1100220110100030102
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Dementia and Neurocognitive Disorders 2011 Volume.10 No. 3 p.102 ~ p.105
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A Case of Nonvasculitic Autoimmune Inflammatory Meningoencephalitis Accompanied by Sjogren¡¯s Syndrome and Elevated Antithyroid Antibodies
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Lee Seong-Joon
Sohn Sung-Yun Lim Tae-Sung Moon So-Young
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Abstract
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Background: Nonvasculitic autoimmune inflammatory meningoencephalitis (NAIM) is known to be one of the causes of potentially reversible dementia. NAIM can be accompanied by various autoimmune diseases.
Methods: A 65 year-old woman had been treated with stable bipolar disorder and presented with rapid cognitive decline, visual hallucination and myoclonus. Anti-thyroid antibodies were elevated. Her symptoms were responsive to steroid therapy. Her diagnostic evaluation also revealed Sjogren¡¯s syndrome. Although her symptoms recovered, a manic episode reappeared and was responsive to psychiatric treatment.
Conclusions: Patients presenting with rapidly progressive dementia should be thoroughly evaluated for the diagnosis of NAIM, a potentially treatable form of dementia, and the possible various underlying autoimmune etiologies.
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KEYWORD
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Nonvasculitic autoimmune inflammatory meningoencephalitis, Sjogren¡¯s syndrome, Steroid responsive encephalopathy associated with autoimmune thyroiditis, Bipolar disorder
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